Electrophoretic study of protein patterns of serum from normal non-pregnant and pregnant women.

The serum protein fractionation has always been a difficulty in routine clinical work. Most of the laboratories employ tedious methods of fractional precipitation with various concentrations of salts to separate albumin from globulin. A simple method of fractionating proteins on filter paper suitable for clinical laboratories has been developed in Germany, the United States and Sweden; Wieland and Fischer (1948), Crem::r and Tiseleus (1950); Durrum (1950), and Turba and Enenkcl (1950). Electrophoresis as a method of separation of protein fractions has proved valuable in analytical studies. Up to the present there have been quite a few reports regarding the utility of this method in investigating the comparative patterns of serum protein. The following paper reports the results obtained of variations in serum albumin and 0:: 1 0:: 2 Band Y . globulins in normal non-pregnant and pregnant women.